All About Alzheimer's Newsletter- Monday 14th April 2025

Welcome to your weekly roundup of insights and stories from All About Alzheimer's.

We strive to bring you the most valuable and relevant information to assist you on your journey as a caregiver.

Table of Contents:

1. Quote of the Day

2. Interesting Stories This Week

3. Caregiver Support Program WAITLIST

4. New Hope in Alzheimer's Treatment

5. Feedback & Engagement

Interesting Stories This Week:

Axsome Asks FDA to Approve Questionable Alzheimer’s Agitation Drug

Actress Pauline Quirke reveals dementia diagnosis

The £20 high street health check that could soon spot signs of Alzheimer's before symptoms strike

Device trial to help protect people with dementia

Condition suffered by 11 million in UK last year 'could be early sign of dementia'

All About Alzheimer’s Caregiver Support Program WAITLIST

Expert-led Training:

• Evidence-Based Approach: Tailored to address the unique needs of those with early-stage Alzheimer's and dementia.

• Global Recognition: Developed in the UK and successfully implemented in 35 countries.

• Carer Advantages: Equips carers with skills to engage in meaningful activities, enhancing relationships with loved ones.

• Enhanced Patient Wellbeing: Participants have shown improvements in mood, communication, social engagement, and overall quality of life.

Ongoing Support Group:

• Expert Access: Regular sessions with dementia care experts to refine your caregiving skills.

• Supportive Community: Join a network of carers who share your experiences and challenges.

• Monthly Activities: Gain access to new exercises each month to keep your caregiving approach effective and engaging.

• Motivation and Inspiration: Share and discover inspiring stories that foster resilience and a sense of shared purpose in the caregiving journey.

Secure your spot early and ensure you are fully equipped to provide the best possible care without sacrificing your own health and happiness.

New Hope in Alzheimer's Treatment: Simplifying the Science Behind Tau Tangles

Alzheimer’s disease is a complex condition that has puzzled scientists for decades. While most treatments have historically focused on one aspect of the disease known as amyloid plaques, recent research is bringing another key player into the spotlight: tau tangles.

What are Tau Tangles?

Imagine the brain as a city with an extensive network of roads (or brain cells). Tau tangles are like roadblocks that disrupt communication and transportation, leading to traffic jams (or disrupted brain function). In Alzheimer’s, these tau tangles accumulate and prevent brain cells from functioning properly, contributing to memory loss and other symptoms.

Why Focus on Tau Tangles?

Researchers have discovered that while clearing up amyloid plaques is beneficial, it’s not enough on its own. Targeting tau tangles might address the disease more directly by unblocking the roads in our brain city analogy, helping to restore the flow of information and keep the brain healthier for longer.

Johnson and Johnson’s Innovative Efforts

Johnson and Johnson are pioneers in this new research area. They are developing treatments that specifically target tau tangles. Their drugs, Posdinemab and JNJ 2056, are designed to latch onto tau tangles and help clear them out, much like a tow truck removes vehicles blocking the road.

What This Means for Patients

If successful, these treatments could change the game for Alzheimer's care. Instead of just slowing down the disease, we might be able to improve the quality of life for patients significantly. Think of it as not only preventing future roadblocks but also clearing existing ones, making the city (or brain) more functional and efficient.

Conclusion

The exploration of treatments targeting tau tangles is an exciting development in Alzheimer’s research. While there's still a way to go before these treatments become widely available, they represent a beacon of hope for millions of patients and their families. By addressing both amyloid plaques and tau tangles, we are moving closer to a comprehensive approach to treating this challenging disease.

We Value Your Feedback

Did you find the insights in the ‘Alzheimer’s Lifeline’ report helpful?

We’re always looking to better support caregivers like you and could really use your help to understand how.

Would you mind taking a quick survey? It’ll just take a few minutes, and your answers will help us shape our support to better suit your needs.